Caution really should be exercised when cholestyramine resin is administered to some nursing mother. The possible deficiency of appropriate vitamin absorption explained inside the “Pregnancy” area could possibly have an effect on nursing infants.
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When the initial dose is properly tolerated, the dose could possibly be increased as desired by one dose/working day (at monthly intervals) with periodic checking of serum lipoproteins. If constipation worsens or the specified therapeutic response just isn't achieved at one particular to 6 doses/working day, mixture therapy or alternate therapy ought to be viewed as. Specific hard work really should be manufactured to stay away from constipation in individuals with symptomatic coronary artery condition. Constipation affiliated with cholestyramine resin may possibly aggravate hemorrhoids.
Most situations of constipation are gentle, transient and controlled with standard therapy. Some people call for a temporary decrease in dosage or discontinuation of therapy.
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There is a chance that prolonged utilization of cholestyramine resin, since it can be a chloride form of anion exchange resin, might generate hyperchloremic acidosis.
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